During the research for his documentary "Weed," Sanjay Gupta interviewed the Figi family, who treats their 5-year-old daughter using a medical marijuana strain high in cannabidiol and low in THC.
There are at least two major active chemicals in marijuana that researchers think have medicinal applications (there are up to 79 known active compounds). Those two are cannabidiol (CBD) — which seems to impact the brain mostly without a high— and tetrahydrocannabinol (THC) — which has pain relieving (and other) properties.
The Figi family's daughter, Charlotte, has Dravet Syndrome, which causes seizures and severe developmental delays.
According to the film, the drug has decreased her seizures from 300 a week to just one every seven days. Forty other children in the state are using the same strain of marijuana (which is high in CBD and low in THC) to treat their seizures — and it seems to be working.
The doctors who recommended this treatment say that the cannabidiol in the plant interacts with the brain cells to quiet the excessive activity in the brain that causes these seizures.
As Gutpa notes, a Florida hospital that specializes in the disorder, the American Academy of Pediatrics, and the Drug Enforcement agency don't endorse marijuana as a treatment for Dravet or other seizure disorders.