Lily-Rose was born on May 27, 1999. Her younger brother, John III, was born three years later on April 9, 2002.
Depp and Paradis never wed and announced their breakup in June 2012 after 14 years together.
"The last couple years have been a bit bumpy," Depp told Rolling Stone in 2013. "At times, certainly unpleasant, but that's the nature of breakups, I guess, especially when there are kiddies involved."
He also discussed the birth of Lily-Rose in the cover story.
"It really was as if a veil was lifted, and things became clearer, and I went, 'Oh, I f---ing get it now! That's what it's for! That's what it's for, this beautiful little creature that I took part in creating, making,'" the actor said. "As long as you have the opportunity to make your kid smile and laugh, and move it forward."