Differin Adapalene Gel .1% Acne Treatment, available on Amazon for $12.88
This gel used to be available only by prescription because it's that powerful, but it's available at beauty aisles now without one. My doctor first prescribed it to me when I was 13 but I promptly stopped using it when my skin became flaky and red almost overnight. I picked it back up at a drugstore a couple of years ago, armed with the knowledge I have now to balance out its drying ingredients.
The Peter Thomas Roth cleanser got rid of a lot of the acne I had on my cheeks and the smaller pimples I had on my chin and jawline, but incorporating this gel afterward is when I saw the biggest decrease in the large, painful, cystic acne that I had on my jawline.
According to Dr. Idriss, the Rx-strength retinol in this, known as adapalene, unclogs pores and prevents breakouts, but it's really strong, so be careful not to use it if you're trying to get pregnant.
It was extremely effective with the worst kind of acne, but I personally had to pair it with a very thick, moisturizing night cream — which acts as the perfect segue to my next point.