Record: 0-5Week 5 result: Lost to the Titans, 37-19Week 6 opponent: vs. Miami Dolphins (in London)One thing to know: With an assist from Jon Gruden, Urban Meyer was briefly not the most embarrassing head coach in the NFL last week. After Gruden's resignation, Meyer leaps back into the top spot.Record: 0-5Week 5 result: Lost to the Vikings, 19-17Week 6 opponent: vs. Cincinnati BengalsOne thing to know: The Lions fell to 0-5 on Sunday after the Vikings hit a game-winning 54-yard field goal as the clock expired. It's the second time in five games Detroit has lost in such a fashion. Someone has got to miss a kick against them eventually.Record: 1-4Week 5 result: Lost to the Patriots, 25-22Week 6 opponent: at Indianapolis ColtsOne thing to know: While they didn't get the win, the Texans should be happy with the performance of quarterback Davis Mills. After a horrid start to the season, Mills looked solid against an intimidating Patriots defense, throwing for 312 yards, three touchdowns, and zero interceptions.Record: 1-4Week 5 result: Lost to the Falcons, 27-20Week 6 opponent: ByeOne thing to know: Zach Wilson has thrown four touchdowns against nine interceptions in his rookie season and is on pace to break the record for most picks thrown by a rookie quarterback. The current holder of that record? Peyton Manning.Record: 1-4Week 5 result: Lost to the Cowboys, 44-20Week 6 opponent: vs. Los Angeles RamsOne thing to know: Running back Saquon Barkley is likely to miss a few games due to an ankle injury suffered against the Cowboys. This comes after missing nearly the entire 2020 season with a torn ACL. Not ideal for the Giants, but pick up Devontae Booker in your fantasy leagues if you can.Record: 1-4Week 5 result: Lost to the Buccaneers, 45-17Week 6 opponent: vs. Jacksonville Jaguars (in London)One thing to know: Since winning their season opener against the Patriots, the Dolphins have been outscored 138-62 in four straight losses. Maybe a trip to London to play the similarly-flailing Jaguars can help them find their step.Record: 2-3Week 5 result: Lost to the Saints, 33-22Week 6 opponent: vs. Kansas City ChiefsOne thing to know: Washington's defense was supposed to be a strong unit this year, but through five games, they've given up more points than any team outside of the Kansas City Chiefs. With games against the Chiefs, Packers, and Buccaneers in the next five weeks, it's tough to imagine those numbers improving any time soon.Record: 1-4Week 5 result: Lost to the Ravens, 31-25Week 6 opponent: vs. Houston TexansOne thing to know: The Colts are 1-4 but still sit in second place in the AFC South standings. They can turn this season around, but the looming threat of the Carson Wentz trade could become a factor later in the season. If Wentz takes 75% of the team's snaps this year, the Colts will send their first-round pick to the Eagles in 2022.Record: 2-3Week 5 result: Beat the Jets, 27-20Week 6 opponent: ByeOne thing to know: After a dismal start to the season, the Falcons have shown some signs of life in recent weeks, winning two of their last three heading into their bye week. In a crowded NFC South, though, 2-3 is still last place.Record: 2-3Week 5 result: Beat the Panthers, 21-18Week 6 opponent: vs. Tampa Bay BuccaneersOne thing to know: The Eagles rallied behind a brilliant performance from Jalen Hurts to earn a comeback victory against the Panthers. If Philadelphia can find a way to survive their upcoming stretch of four weeks that includes the Buccaneers, Raiders, and Chargers with their season still intact, they'll have a good chance at making a run to the playoffs with a much more manageable second-half schedule.Record: 2-3Week 5 result: Beat the Lions, 19-17Week 6 opponent: at Carolina PanthersOne thing to know: No team in the NFL may have been hurt more by their kickers in recent history than the Minnesota Vikings. When Greg Joseph stepped up and drilled a 54-yard field goal to beat the Lions on Sunday, it was as deserved a victory as you will ever see.Record: 2-3Week 5 result: Beat the Broncos, 27-19Week 6 opponent: vs. Seattle SeahawksOne thing to know: Rookie Najee Harris had the best game of his young career against the Broncos, going for 142 total yards and a touchdown. While Big Ben is still pretty much a statue at quarterback, if Harris and the offensive line can get the ball moving, the Steelers can contend.Record: 2-3Week 5 result: Lost to the Rams, 26-17Week 6 opponent: at Pittsburgh SteelersOne thing to know: Russell Wilson is out for at least a month after injuring his fingers against the hand of Rams defender Aaron Donald, meaning Geno Smith will be playing quarterback for the Seahawks for their next stretch. This is certainly not what the NFL schedule makers planned when they put Seattle in primetime for the next two weeks.Record: 2-3Week 5 result: Beat the Texans, 25-22Week 6 opponent: vs. Dallas CowboysOne thing to know: The Patriots erased a 22-9 second-half deficit to beat the Texans last week, but they'll have to get scoring a bit faster with the Cowboys coming to town on Sunday.Record: 3-2Week 5 result: Beat the Raiders, 20-9Week 6 opponent: vs. Green Bay PackersOne thing to know: The Bears defense stepped up in a big way against the Raiders, holding Derek Carr to just 206 yards in the air after he had averaged 350 yards per game over the first four weeks. A similar challenge awaits this weekend against Aaron Rodgers.Record: 3-2Week 5 result: Lost to the Packers, 25-22Week 6 opponent: at Detroit LionsOne thing to know: Bengals kicker Evan McPherson had a tough day on Sunday, missing two potential game-winning field goals against the Packers and celebrating too early in overtime as his kick bounced off the upright.Record: 2-3Week 5 result: Lost to the Cardinals, 17-10Week 6 opponent: ByeOne thing to know: Trey Lance struggled throwing the ball in his first game as a starter, completing just 15 of his 29 passes for 192 yards and a pick. He made up for it on the ground, leading the 49ers' rushing attack with 89 yards on 16 carries.Record: 3-2Week 5 result: Beat the Washington Football Team, 33-22Week 6 opponent: ByeOne thing to know: Jameis Winston bounced back with another stellar game against Washington that included a hail mary touchdown to close out the first half and a rainbow touchdown to Deonte Harris over the entire Washington defense. Eat a W, my guy.Record: 3-2Week 5 result: Lost to the Steelers, 27-19Week 6 opponent: vs. Las Vegas RaidersOne thing to know: After allowing just 26 points over their first three games of the season, the Broncos defense has given up 50 points over the past two weeks.Record: 3-2Week 5 result: Lost to the Bears, 20-9Week 6 opponent: at Denver BroncosOne thing to know: With the departure of head coach Jon Gruden after a trove of offensive emails resurfaced, special teams coordinator Rich Bisaccia is taking over the top job in Las Vegas.Record: 3-2Week 5 result: Lost to the Eagles, 21-18Week 6 opponent: vs. Minnesota VikingsOne thing to know: Star running back Christian McCaffrey should be able to get back out on the field this week after missing a few games to injury. The news comes as a relief to Panthers fans and fantasy players that had the first overall pick in this year's draft all across the country.Record: 3-2Week 5 result: Beat the Jaguars, 37-19Week 6 opponent: vs. Buffalo BillsOne thing to know: Derrick Henry is still the most unstoppable rusher in the league, averaging 128 rushing yards per game through five weeks.Record: 2-3Week 5 result: Lost to the Bills, 38-20Week 6 opponent: at Washington Football TeamOne thing to know: The brilliance of the Chiefs offense was able to cover up some weaknesses over the past few years, but the team's defense, which has given up more points than any other defense in the league, may be too bad for Patrick Mahomes and company to make up the difference this year.Record: 3-2Week 5 result: Lost to the Chargers, 47-42Week 6 opponent: vs. Arizona CardinalsOne thing to know: The Cleveland Browns are 3-2, but with both losses coming in close contests against potential Super Bowl contenders, there's little reason to believe they can't make a run.Record: 4-1Week 5 result: Beat the Browns, 47-42Week 6 opponent: at Baltimore RavensOne thing to know: Justin Herbert is throwing his way into the record books. With five touchdowns on Sunday, Herbert hit 13 touchdown passes on the season through five weeks, the fourth most ever for a first- or second-year quarterback. All three players ahead of Herbert on that list — Dan Marino, Kurt Warner, and Patrick Mahomes — were named MVP in the year of their hot start.Record: 4-1Week 5 result: Beat the Bengals, 25-22Week 6 opponent: at Chicago BearsOne thing to know: Kicker Mason Crosby missed three potential game-winning field goals before finally sealing the win for the Packers in overtime against the Bengals. Few kickers in the league have more job security than Crosby, and his sure-footed 49-yarder, even during a career-terrible day, shows why.Record: 4-1Week 5 result: Beat the Giants, 44-20Week 6 opponent: at New England PatriotsOne thing to know: The Cowboys averaged more than 40 points per game during their three-game homestand that ended on Sunday with a win over the Giants. If Dallas can run through the season and secure home-field advantage in the playoffs, they'll be a tough out for any team in the NFC.Record: 4-1Week 5 result: Beat the Colts, 31-25Week 6 opponent: vs. Los Angeles ChargersOne thing to know: Lamar Jackson accounted for 499 of the Ravens' 523 yards in their comeback win over the Colts on Monday night, including throwing for a career-high 442 yards in the air. Good luck trying to stop him.Record: 4-1Week 5 result: Beat the Seahawks, 26-17Week 6 opponent: at New York GiantsOne thing to know: The Rams win over the Seahawks wasn't exactly pretty, but it got the job done. As things stand, the Rams are 4-1, and their defense isn't even yet playing up to its full potential.Record: 5-0Week 5 result: Beat the 49ers, 17-10Week 6 opponent: at Cleveland BrownsOne thing to know: The last remaining undefeated team put up a bit of a clunker on Sunday but was still able to come out on top against the 49ers. Kyler Murray is still the leading MVP candidate through five weeks, though the race certainly tightened a bit this week.Record: 4-1Week 5 result: Beat the Dolphins, 45-17Week 6 opponent: at Philadelphia EaglesOne thing to know: Tom Brady will get his chance for revenge against the Eagles after losing to Philadelphia in Super Bowl LII. Coming off a game where he threw for 411 yards and five touchdowns, the Eagles defense better be ready.Record: 4-1Week 5 result: Beat the Chiefs, 38-20Week 6 opponent: at Tennessee TitansOne thing to know: After throttling the Chiefs in primetime, the Buffalo Bills look like the team to beat in the NFL. Josh Allen played like an MVP, the defense stepped up on several occasions, and head coach Sean McDermott left Kansas City in a daze.