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An affordable <keyword id="9107118" type="General" weightage="20" keywordseo="tuberculosis-testing" source="Orion">tuberculosis testing</keyword> technology that can detect the disease using a patient's sputum for just Rs 35 has been developed by apex medical research body <keyword id="19918794" type="General" weightage="20" keywordseo="ICMR" source="keywords">ICMR</keyword>'s regional centre in Assam's Dibrugarh. The 'A <keyword id="19986036" type="General" weightage="20" keywordseo="CRISPR" source="keywords">CRISPR</keyword> case-based TB detection system' is light, portable and involves three steps of testing. Over 1,500 samples can be tested in one single run in around two-and-half hours, ICMR sources said. Conventional diagnostic techniques for TB commonly rely on culture, which requires 42 days to confirm as TB negative, microscopy, and nucleic acid-based methods. These are also time-consuming and may require sophisticated equipment. An official said, "<keyword id="19992404" type="General" weightage="100" keywordseo="Tuberculosis" source="keywords">Tuberculosis</keyword> (TB) remains a global health challenge, necessitating the development of accurate and rapid diagnostic tools for effective disease management. Current <keyword id="22921102" type="General" weightage="20" keywordseo="diagnostic-methods" source="keywords">diagnostic methods</keyword> often exhibit limitations in terms of sensitivity, specificity, speed and cost, emphasising the need for innovative approaches". Additionally, some molecular diagnostic methods, while offering improved sensitivity, may lack the desired specificity or face challenges associated with cost and ease of handling. "Considering these problems, the CRISPR-Cas12a-based molecular diagnostic system 'GlowTBPCRKit' coupled with an amplification step (using thermal cycler) and the '<keyword id="22921103" type="General" weightage="20" keywordseo="RapidGlow-device" source="keywords">RapidGlow device</keyword>' provides a promising solution," the official said. The Indian Council of Medical Research (ICMR) has now invited Expression of Interest (EoI) from eligible organisations, companies, manufacturers for undertaking 'Transfer of Technology' for commercialisation of the 'A CRISPR case-based TB detection system' for the detection of <keyword id="20115212" type="General" weightage="20" keywordseo="Mycobacterium-tuberculosis" source="keywords">Mycobacterium tuberculosis</keyword>. The ICMR-RMRCNE institute will provide expert guidance and technical support for the production of 'A CRISPR Cas based TB detection system' in all phases. Such technical oversight by the institute would accelerate the development of the product and its commercialisation. The ICMR would also provide technical support through its team of experienced scientists in study, planning, product development, development of study protocol, results or data analysis, outcome assessment, safety and efficacy assessment, product improvement, etc., if deemed fit upon the mutual understanding between ICMR and collaborative company. The apex health research body through its institutes would provide support and facilitation to conduct the research and development or clinical study of new technology or product in India through its affiliates or institutes, in collaboration with the company and institutions in a professional and mutually agreed upon manner and timelines.

ICMR's regional centre develops technology that can test for tuberculosis in just Rupees 35!

The Indian Council of Medical Research Director General Dr Rajiv Bahl on Monday criticised a recently published study on the long-term safety analysis of the <keyword id="9485939" type="General" weightage="100" keywordseo="covaxin" source="Orion">Covaxin</keyword> in adults and adolescents for its poor methodology and design, and clarified the article misleadingly and erroneously "acknowledges" <keyword id="19918794" type="General" weightage="20" keywordseo="ICMR" source="keywords">ICMR</keyword>. Dr Bahl said the study had no control arm of unvaccinated individuals for comparing the rates of events between the vaccinated and unvaccinated groups. Hence, the reported events in the study cannot be linked or attributed to COVID-19 vaccination. He added that the ICMR is not associated with the study and has not provided any financial or technical support for the research. The ICMR DG has written a letter to the authors of the paper and Editor of the journal to immediately remove the acknowledgement to ICMR and publish an erratum. A research paper, titled 'Long-Term Safety Analysis of the BBVl52 <keyword id="21730391" type="General" weightage="20" keywordseo="coronavirus-vaccine" source="keywords">Coronavirus Vaccine</keyword> in Adolescents and Adults: Findings from a l-Year Prospective Study in North India' stated that nearly one-third of the 926 participants in the study who received Bharat Biotech's anti-Covid vaccine Covaxin reported 'adverse events of special interest,' or AESI. Dr Bahl said that ICMR was acknowledged for research support without any prior approval of or intimation to ICMR, which is inappropriate and unacceptable. He stated that ICMR cannot be associated with this poorly designed study which purports to present a "safety analysis" of Covaxin due to several critical flaws. He said the study does not even provide background rates of observed events in the population, making it impossible to assess the change in incidence of observed events in the post-vaccination period. Baseline information of study participants is missing. The study tool used is inconsistent with 'Adverse Events of Special Interest (AESI)' as defined in the reference provided in the paper for AESI. The method of data collection has a high risk of bias, he said. Study participants were contacted telephonically one year after vaccination and their responses were recorded without any confirmation with clinical records or by physician examination, he pointed out. Dr Bahl also noted that similar acknowledgements to ICMR have been made in previous papers without permission, raising concerns about the authors' practices. "The authors have been urged to immediately rectify the acknowledgment to ICMR and publish an erratum. Additionally, they are asked to address the methodological concerns raised. Failure to do so may prompt ICMR to consider legal and administrative action," he said. The Editor has been asked to retract the paper which implicitly makes conclusions on <keyword id="21495684" type="General" weightage="20" keywordseo="vaccine-safety" source="keywords">vaccine safety</keyword> which are not supported by evidence. The study, conducted by researchers from the Banaras Hindu University from January 2022 to August 2023, stated that nearly 50 per cent of 926 study participants in the study complained of infections during the follow-up period, predominated by viral upper respiratory tract infections. Serious AESI, which included stroke and Guillain-Barre syndrome, were reported in one per cent of individuals, the study, which looked at long-term safety of the BBV152 (Covaxin) vaccine in adolescents and adults, claimed. The study involved 635 adolescents and 291 adults, who received the BBV152 vaccine.

BHU study on Covaxin side effects poorly designed, critically flawed: ICMR Director General

A sperm or <keyword id="22773682" type="General" weightage="20" keywordseo="egg-donor" source="keywords">egg donor</keyword> has no legal right on the child, and cannot claim to be its <keyword id="22773683" type="General" weightage="100" keywordseo="biological-parent" source="keywords">biological parent</keyword>, the Bombay <keyword id="19900812" type="General" weightage="20" keywordseo="high-court" source="keywords">High Court</keyword> held on Tuesday, while allowing a 42-year-old woman visitation rights to her five-year-old twin daughters. The woman, in her plea, said her daughters, born via <keyword id="20302787" type="General" weightage="20" keywordseo="surrogacy" source="keywords">surrogacy</keyword>, were living with her husband and younger sister, who was the egg donor. The petitioner's husband had claimed since his sister-in-law was the egg donor, she had a legitimate right to be called a biological parent of the twins, and that his wife had no right over them. A single bench of Justice Milind Jadhav, however, refused to accept this contention, citing that though the petitioner's younger sister was the egg donor, she has no legitimate right to claim that she is a biological parent of the twins. The court said the role of the younger sister is that of an egg donor, rather, a voluntary donor, and at the most, she may qualify to be a genetic mother and nothing more. An advocate appointed to assist the court in the matter informed it that since the estranged couple's surrogacy agreement took place in 2018, when the Surrogacy (Regulation) Act 2021 had not come into force, the guidelines issued by the <keyword id="19914690" type="General" weightage="20" keywordseo="Indian-Council-of-Medical-Research" source="keywords">Indian Council of Medical Research</keyword> (ICMR) in 2005 would regulate the agreement. As per a rule of the guidelines, the donor and the surrogate mother have to relinquish all parental rights, the court noted, adding that in the present case, the twins would be the daughters of the petitioner and her husband. "Under the guideline, it is clearly stated that the sperm/oocyte (egg) donor shall not have parental rights or duties in relation to the child and in that view of the matter, the younger sister of the petitioner can have no right whatsoever to intervene and claim to be the biological mother of the twin daughters," the high court said. As per the plea, the couple could not conceive naturally, and the petitioner's sister volunteered to donate her eggs. In December 2018, the babies were conceived by a surrogate woman and the twin girls were born in August 2019. In April 2019, the sister and her family met with a road accident, and her husband and daughter were killed. The petitioner lived with her husband and twin daughters from August 2019 to March 2021. Following a marital discord in March 2021, the husband moved into another flat with the children without informing his wife. The man claimed that his wife's sister (the egg donor) had been depressed after the road accident and started living with him to take care of the twins. The petitioner filed a police complaint and an application before a local court, seeking interim visitation rights to her daughters. The local court rejected her application in September 2023, following which she approached the high court. The wife said her sister had only donated her eggs and was not the surrogate mother, and hence, she had no legal right or role in the lives of the twins. The high court, in its order, noted that the surrogacy agreement of 2018 between the intending parents, the surrogate mother and the doctor is signed by the petitioner, her husband and the doctor. "It is seen that the petitioner (wife) and Respondent No. 1 (husband) are recognised as the intending parents. At least to a naked eye, there is no ambiguity whatsoever while observing and even concluding that it is the petitioner along with Respondent No. 1 who signed the surrogacy agreement as intending parents," it said. Justice Jadhav held that the lower court order denying visitation rights to the wife was passed without proper application of mind and is unsustainable and quashed it. The court directed the husband to give physical access and visitation rights of the twins to the petitioner for three hours every weekend.

Sperm or egg donor has no legal right on child, can't claim to be biological parent, says high court

Opening your social media has become an unintentional gamble in recent times. You either stumble upon an adorable video of someone’s pet, or get blasted with the most diabolical political opinion you’ve ever had the misfortune of witnessing. However, such apps have also fuelled a sort of food revolution among the masses recently, with more and more people looking out for <keyword id="21712333" type="General" weightage="20" keywordseo="healthier-food-alternatives" source="keywords">healthier food alternatives</keyword> to supplement their main meals and guilty snacking habits. While this is undoubtedly a great step considering how much of our health hinges on our food intake, one question has been increasingly puzzling everyone out of their minds: what exactly is healthy anymore? To get to the bottom of the matter, we looked at the latest <keyword id="21712334" type="General" weightage="20" keywordseo="Indian-dietary-guidelines" source="keywords">Indian dietary guidelines</keyword> released by the Indian Council of Medical Research (<keyword id="19918794" type="General" weightage="20" keywordseo="ICMR" source="keywords">ICMR</keyword>), and our findings left the office erupting in groans. According to the medical board, some examples of <keyword id="21712332" type="General" weightage="100" keywordseo="ultra-processed-food" source="keywords">ultra-processed food</keyword> include commercially produced <keyword id="93269" type="General" weightage="20" keywordseo="bread" source="Orion">bread</keyword>, breakfast cereals and even other staples such as refined flour and <keyword id="6446947" type="General" weightage="20" keywordseo="butter" source="Orion">butter</keyword>. <cmsannotation type="cmsannotation" annotationid="What counts as &quot;ultra-processed&quot;?" comment="subhead" text="What counts as &quot;ultra-processed&quot;?">What counts as "ultra-processed"?</cmsannotation> Before you throw your snack out the window, let’s understand what “ultra-processed” means. Considering that we don't live in a utopia where we can just head out and bite the stalks off a wheat plant for sustenance, most of the food we consume has to undergo some processing to make them suitable for consumption. Thus, grains are grinded into flour, fruits may have to be refrigerated and milk pasteurised — all forms of processing that make these healthy food items ready to eat. However, in the pursuit to improve taste, appearance or shelf-life, many companies subject their food products to extensive industrial processing by integrating a concerning amounts of additives such as preservatives, sweeteners, colourings, flavourings, emulsifiers, and other substances that would not typically find in an everyday kitchen. These are massive no-nos, as far as the ICMR is concerned. <cmsannotation type="cmsannotation" annotationid="Heart attack, stroke, obesity" comment="subhead" text="Heart attack, stroke, obesity">Heart attack, stroke, obesity</cmsannotation> These ultra-processed foods (UPFs) also tend to be excessively high in fats and unusually low in fibres and essential <keyword id="19896135" type="General" weightage="20" keywordseo="nutrients" source="keywords">nutrients</keyword>. Studies have shown that a diet that is rich in such items can lead to obesity, hasten ageing, and are associated with a higher risk of heart attack, strokes, diabetes and poorer overall health. Perhaps the worst problem with them is that such foods are typically very cheap and easily accessible, leading them to be a popular choice for the masses. Further, enriching UPFs with nutrients still does nothing to make them wholesome or healthy. The ICMR advises against overconsumption of “level C” foods, which means that these edibles are high in sugars and salts and/or have been subjected to extensive techniques that break down nutrients such as vitamins, minerals and fibre in them. Such processes include over-refining of flours, juicing of fruits, subjecting the food items to high temperatures and pressures, and canning and preservation. <cmsannotation type="cmsannotation" annotationid="List of foods classified as ultra-processed" comment="subhead" text="List of foods classified as ultra-processed">List of foods classified as ultra-processed</cmsannotation> According to the ICMR, Group C food items include commercially produced bread, breakfast cereals, cakes, chips, biscuits, fries, jams, sauces, mayonnaise, commercially produced ice cream, protein packs powders, peanut butter, soy chunks, tofu, frozen foods with additives, commercially produced cheese, butter, paneer with additives, meats, plant-based meats, refined flours of cereals, millets and legumes, energy drinks, health drinks added to milk, beverages and fruit juices. The group also includes many culinary ingredients such as cooking oils, refined sugars, salt and spices, since cosmetic food additives such as artificial colours and emulsifiers are often used in their processing. As social media drives a growing interest in healthier eating habits, it becomes crucial for consumers to discern and avoid these heavily processed items, favouring more natural and minimally processed alternatives to promote better overall health. However, moderation is perhaps the word of the year, and it would do well to learn about the stuff that goes inside our bodies, rather than live in fear of them. The full ICMR report can be accessed <a href="https://main.icmr.nic.in/sites/default/files/upload_documents/DGI_07th_May_2024_fin.pdf" data-type="tilCustomLink">here</a>.

Bread, butter, milk-based health drinks, cooking oils classified as ultra-processed food, ICMR advises restriction

The <keyword id="6364555" type="General" weightage="50" keywordseo="indian-council-of-medical-research" source="Orion">Indian Council of Medical Research</keyword> (<keyword id="6364396" type="General" weightage="100" keywordseo="icmr" source="Orion">ICMR</keyword>) has sought proposals in <keyword id="619017" type="General" weightage="80" keywordseo="stillbirths" source="Orion">stillbirths</keyword> under the <keyword id="15545302" type="General" weightage="50" keywordseo="icmr-task-force-programme" source="Orion">ICMR Task Force Programme</keyword> for research funding. The concept proposals with specific objectives and scientific questions should be submitted online by December 30, 2022, by 5 pm, it said. "<keyword id="113952" type="General" weightage="50" keywordseo="stillbirth" source="Orion">Stillbirth</keyword>s are a hidden tragedy that impacts millions of women and families across the globe daily. The stillbirth rate may be one of the indicators of the quality of a country's medical system. Stillbirth has multifactorial etiologies. Early identification of risk factors for stillbirth and appropriate antenatal management may reduce preventable stillbirths and improve the pregnancy outcomes," the ICMR said in a release. The ICMR Call for Proposals in Stillbirths, under the ICMR Task Force Programme, further states that the initiative is in line with the government's aim of bringing the number of stillbirths in the country down to single digits by 2030. "The INAP by the Government of India now plans to bring down stillbirths to single digits by 2030. There is a need for research into the causes of stillbirth and effective prevention and treatment of these causes identifying research challenges. The ICMR expert group on Still Births has identified three key thematic areas to prioritise and articulate research challenges," the ICMR said. "The concept proposal can be submitted for financial support through online mode only by scientists/ professionals, who have regular employment in medical institutes/research institutes/ universities/colleges/recognised research and development laboratories/government and semi-government organisations and NGOs (documentary evidence of their recognition including DSIR certificate should be enclosed with the proposal)," the ICMR release further stated. SEE ALSO: <a target="_blank" class="c-link c-message_attachment__title_link" href="https://www.businessinsider.in/science/health/news/cervical-cancer-4th-most-common-among-women-policymakers-should-urgently-move-to-eliminate-who/articleshow/95580233.cms">Cervical cancer 4th most common among women, policymakers should urgently move to eliminate: WHO</a> <a target="_blank" class="c-link c-message_attachment__title_link" href="https://www.businessinsider.in/science/health/news/covid-19-infection-may-reactivate-several-latent-viruses-in-body-study/articleshow/95581176.cms">Covid-19 can reactivate latent viruses lurking in the body's cells</a>

Stillbirths are a hidden tragedy says ICMR as it seeks research funding

Almost 4 lakh diarrhoeal disease deaths can be averted if '<keyword id="7834202" type="General" weightage="100" keywordseo="jal-jeevan-mission" source="Orion">Jal Jeevan Mission</keyword>' meets its target of providing clean water to all rural households, according to a new study by the <keyword id="6356311" type="General" weightage="50" keywordseo="world-health-organisation" source="Orion">World Health Organisation</keyword>. The government launched the Jal Jeevan Mission (JJM) in 2019, a nationwide programme that aims to provide all houses in rural areas with safe and adequate drinking water through individual tap connections by next year. The <keyword id="43588" type="General" weightage="50" keywordseo="world-health-organization" source="Orion">World Health Organization</keyword> (WHO) was requested by the Ministry of Drinking Water and Sanitation to conduct a study to assess potential health gains and associated cost savings due to increased access in safely-managed drinking water services in <keyword id="3658" type="General" weightage="80" keywordseo="india" source="Orion">India</keyword>. The study found that, on an estimate, if the Jal Jeevan Mission provided safely-managed drinking water to all of India, this would result in averting almost 4 lakh deaths caused by diarrhoeal disease. According to official figures, till now 62 per cent rural households have been provided with tap water connection. "With universal coverage of safely-managed drinking water in India, almost 14 million DALYS (Disability adjusted life years) from the diarrhoeal disease are estimated to be averted, resulting in estimated cost savings of up to USD 101 billion," the study said. Also, the study said that providing a tap connection to every household would result in significant time saved on water collection (66.6 million hours each day), especially among women. Presenting the research findings, Richard Johnston, co-lead of WHO/UNICEF Joint Monitoring Programme for Water Supply, Sanitation and Hygiene, said if the world achieves its Sustainable Development Goals (SDG) targets of drinking water and sanitation, it will be because of India. "There are two reasons for it -- population and size -- as India is the country with the largest population in the world so what happens in India is important for the world but it is also because India is demonstrating what can be done and what is possible when it makes commitments and investments," he said. Dr Rajiv Bahl, Director General of the <keyword id="6364555" type="General" weightage="50" keywordseo="indian-council-of-medical-research" source="Orion">Indian Council of Medical Research</keyword>, said these findings are plausible. "We must understand that these are gross underestimates of the total benefits of providing safe water not only because these benefits go beyond health and they affect many communicable and non-communicable diseases. And even malnutrition, which is a big issue for us as they are all also related to water, so we must consider these just modest assumptions and tip of the iceberg," Bahl said. WHO estimation of health impacts is based on comparative risk assessment (CRA) methods, which are used extensively in the burden of disease assessments (Ezzati 2002, Pruss-Ustun 2019). The analysis estimated potential health gains from the Mission by comparing two scenarios. The JJM scenario assumed that coverage of safely managed drinking water services in India increases linearly from baseline levels to 100 per cent coverage at the end of the programme, whereas, the business-as-usual scenario assumed improvements in coverage rates are in line with historical annual rates of 0.5 percentage points change per year. For the economic analysis, the value per DALY averted from the JJM initiative was based on an approach described in the 2001 report of the WHO's Commission on Macroeconomics and Health which assigned each life year a value of three times the GDP per capita. SEE ALSO: <a target="_blank" class="c-link c-message_attachment__title_link" href="https://www.businessinsider.in/sustainability/news/the-worlds-oceans-last-month-were-warmer-than-any-other-may-since-the-beginning-of-the-19th-century/articleshow/100875382.cms">The world's oceans last month were warmer than any other May since the beginning of the 19th century</a> <a target="_blank" class="c-link c-message_attachment__title_link" href="https://www.businessinsider.in/business/auto/news/bmw-m2-launched-in-india-here-are-some-of-the-top-sports-cars-available-in-the-country/slidelist/100874746.cms">BMW M2 comes to India: Here’s how it compares with top sports cars available here</a>

Almost 4 lakh diarrhoeal disease deaths can be averted if Jal Jeevan Mission meets target: WHO study

The condition of a young woman of African origin, who is the sixth reported case of <keyword id="7616951" type="General" weightage="100" keywordseo="monkeypox" source="Orion">monkeypox</keyword> in Delhi, is stable, sources said. The patient is admitted to the <keyword id="6394484" type="General" weightage="80" keywordseo="lnjp-hospital" source="Orion">LNJP Hospital</keyword> here. "A total of six cases of monkeypox have been reported in Delhi so far. The latest is a young woman of African origin. Her condition is stable at present," a source said. The six cases comprise three men and three women. "The early five cases have been treated and discharged," a senior doctor said. Monkeypox is a viral zoonotic disease having common symptoms such as fever, skin lesions, lymphadenopathy, headache, muscle aches, exhaustion, chills or sweats and sore throat and cough. According to a study done recently by the Lok Nayak Jai Prakash Narayan Hospital (LNJP) and the <keyword id="6364555" type="General" weightage="50" keywordseo="indian-council-of-medical-research" source="Orion">Indian Council of Medical Research</keyword> (<keyword id="6364396" type="General" weightage="50" keywordseo="icmr" source="Orion">ICMR</keyword>), all the first five cases had presented with "mild to moderate grade intermittent fever, myalgia (muscle pain) and lesions on the genitals, groins, lower limb, trunk and upper limb". Four cases had non-tender firm lymphadenopathy (swelling of lymph nodes). No secondary complications or sexually transmitted infections were recorded in these cases except for Hepatitis B in one case, it had said. In Delhi, the first case of monkeypox was reported on July 24. Delhi government-run LNJP Hospital has been made the nodal facility to treat patients with this viral infection. SEE ALSO : <a target="_blank" class="c-link c-message_attachment__title_link" href="https://www.businessinsider.in/india/news/exams-results-major-cause-of-anxiety-among-school-students-ncert-survey/articleshow/94041766.cms">Exams, results major cause of anxiety among school students: NCERT survey</a> <a target="_blank" class="c-link c-message_attachment__title_link" href="https://www.businessinsider.in/stock-market/news/tamilnad-mercantile-bank-ipo-is-subscribed-1-53-on-day-2-grey-market-premiums-fall/articleshow/94032064.cms">Tamilnad Mercantile Bank IPO is subscribed 1.53% on day 2, grey market premiums fall</a>

Sixth monkeypox case: Patient in stable condition at LNJP Hospital

(Eds: With file pics) Hyderabad, Two major vaccine makers from Hyderabad, <keyword id="1379126" type="General" weightage="20" keywordseo="Biological-E" source="Orion">Biological E</keyword> Ltd and <keyword id="149108" type="General" weightage="100" keywordseo="bharat-biotech" source="Orion">Bharat Biotech</keyword>, together are holding about 250 million doses of COVID-19 vaccines ready to dispatch as and when orders are received. According to respective company sources, Biological E is holding 200 million doses of its COVID-19 vaccine <keyword id="11370342" type="General" weightage="80" keywordseo="corbevax" source="Orion">Corbevax</keyword> while Bharat Biotech is sitting on a stockpile of 50 million doses of Covaxin. Dr Vikram Paradkar, Executive Vice President (Manufacturing), Biological E, said the firm produced about 30 crore doses of Corbevax in total, abiding by the vaccine manufacturing commitment to the Central government. In March '22, Biological E successfully supplied 10 crore doses to the government. "Currently, we have approximately 20 crore (200 million) doses that are fully tested and ready for supply, as and when we receive orders. Additionally, we manufactured 20 crore doses equivalent of the antigen which will help us ramp up the manufacturing of the Corbevax finished product quickly," Paradkar told PTI. The vaccine has been developed by Biological E in collaboration with Texas Children's Hospital Center for Vaccine Development (Texas Children's CVD) and Baylor College of Medicine (Baylor) in Houston, Texas, USA. He further said Biological E can begin with the additional vaccine supplies within eight weeks of future orders and can manufacture and supply approximately 10 crore doses of Corbevax on a monthly basis as per its qualified manufacturing capacity. Bharat Biotech sources said the vaccine maker has more than 50 million doses of Covaxin readily available in vials, and over 200 million doses as drug substance. "Additional production capacity is also available to meet product demand," they said adding fresh stocks of the vaccine are available and ready for supplies. Covaxin, India's indigenous COVID-19 vaccine, was developed in collaboration with the <keyword id="6364555" type="General" weightage="50" keywordseo="indian-council-of-medical-research" source="Orion">Indian Council of Medical Research</keyword> (ICMR) - National Institute of Virology (NIV). Due to lack of product demand, production stoppage of Covaxin was initiated earlier this year and also the 50 million doses in vials are set to expire during early 2023, resulting in losses to the company, sources had earlier said. SEE ALSO: <a href="https://www.businessinsider.in/india/news/rise-in-active-covid-19-cases-in-bihar-no-need-for-panic-says-expert/articleshow/96561025.cms">Rise in active COVID-19 cases in Bihar; no need for panic, says expert</a> <a href="https://www.businessinsider.in/science/health/news/covid-19-nasal-vaccine-bharat-biotechs-incovacc-is-the-first-approved-intranasal-vaccine-in-the-world/slidelist/96542239.cms">All you need to know about the world’s first Covid-19 nasal vaccine - iNCOVACC</a>

Biological E, Bharat Biotech together sitting on stockpile of 250 million COVID vaccine doses

A total of 7.9 per cent of all cancer cases between 2012-19 were found in children below 14 years, a report prepared by the <keyword id="6364555" type="General" weightage="20" keywordseo="Indian-Council-of-Medical-Research" source="Orion">Indian Council of Medical Research</keyword> said. "Clinicopathological Profile of Cancers in India: A Report of the Hospital-Based Cancer Registries, 2021", consolidates data collected during the period across 96 hospital-based cancer registries under the <keyword id="421743" type="General" weightage="20" keywordseo="national-cancer-registry-programme" source="Orion">National Cancer Registry Programme</keyword> (NCRP). The data pertains to all diagnosed and treated cases of confirmed malignancies reported to these centres across the country The country registered 13,32,207 cases of cancer during 2012-19. Of these, 6,10,084 were included for analysis, based on the completeness and quality of data. Childhood cancers rank ninth as a leading cause of childhood diseases at the global level, accounting for 11.5 million of the <keyword id="8118522" type="General" weightage="20" keywordseo="Disability-Adjusted-Life-Years" source="Orion">Disability Adjusted Life Years</keyword> (DALYs). In India, according to a recent NCRP report, the proportion of childhood cancers (0-19 years), relative to cancers in all age groups, was found to range from 1 per cent to 4.9 per cent. Delhi reported the highest age-adjusted incidence rate (AAR) of 203.1 per million in boys and 125.4 per million in girls. Leukaemia accounted for nearly half of all the childhood cancers in both genders in the 0-14 years age group (46.4 per cent in boys and 44.3 per cent in girls). The other common childhood cancer in boys was lymphoma (16.4 per cent), while in girls, it was malignant bone tumour (8.9 per cent). Childhood cancers are presented for two age groups: 0-14 years and 0-19 years to enable national and international comparison, and classified according to the International Classification of Childhood Cancer. Apart from childhood cancer, the <keyword id="6958288" type="General" weightage="20" keywordseo="ICMR-report" source="Orion">ICMR report</keyword> says that cancers in sites associated with tobacco use comprised 48.7 per cent of cancers among males and 16.5 per cent among females. The relative proportion of site-specific cancers was higher in males than females except for thyroid cancer (2.5 per cent in females versus 1 per cent in males) and gall bladder cancer (3.7 per cent in females versus 2.2 per cent in males). Among all the cancers, the highest proportion of distant metastasis at presentation was seen in patients with lung cancer (49.2 per cent males and 55.5 per cent females), followed by gall bladder cancer (40.9 per cent males and 45.7 per cent females) and prostate cancer (42.9 per cent). The <keyword id="6364396" type="General" weightage="20" keywordseo="ICMR" source="Orion">ICMR</keyword> reports suggested that chemotherapy was still the most typical treatment modality for many cancers, regardless of the clinical extent of disease at presentation, including cancers of the liver, gall bladder, stomach, lung, and childhood cancers. SEE ALSO <a href="https://www.businessinsider.in/india/news/highlights-of-prime-minister-narendra-modis-speech-at-the-unga-today/articleshow/86510462.cms">Indian Prime Minister Narendra Modi makes his points on China, Afghanistan and Pakistan at the United Nations General Assembly</a> <a href="https://www.businessinsider.in/thelife/personalities/freshworks-ceo-girish-mathrubootham-shares-someone-said-i-will-be-nothing-but-a-rickshaw-puller/articleshow/86507840.cms">WATCH: "Someone said I am good enough to be a rickshaw puller," shares Freshworks CEO Girish Mathrubootham in a candid chat</a>

Out of all cancer cases, 7.9% were found in children below 14 years, reveals ICMR report

India's drug regulator has given approval for a study to be conducted by the <keyword id="93589" type="ORGANIZATION" weightage="20" keywordseo="Christian-Medical-College">Christian Medical College</keyword> (CMC), Vellore on mixing of COVID-19 vaccines <keyword id="9485939" type="LOCATION" weightage="20" keywordseo="covaxin">Covaxin</keyword> and Covishield, official sources said on Wednesday. An expert panel of the <keyword id="170943" type="ORGANIZATION" weightage="20" keywordseo="Central-Drugs-Standard-Control-Organisation">Central Drugs Standard Control Organisation</keyword> (CDSCO) on July 29 had recommended granting permission for conducting the study. The trial will involve 300 healthy volunteers. "The aim of the study is to assess the feasibility on whether a person can be given two different vaccine shots -- one each of Covishield and Covaxin -- to complete the inoculation course," a source said. Separately, a recent study by the Indian Council of Medical Research (ICMR) involving 98 people, 18 of whom had inadvertently received Covishield as the first dose and Covaxin as the second in <keyword id="413944" type="PERSON" weightage="20" keywordseo="uttar">Uttar</keyword> Pradesh, showed that combining these two COVID-19 vaccines elicited better immunogenicity than two doses of the same vaccine. The study also found that immunisation with combination of Covishield and Covaxin was safe and the adverse effects were also found to be similar when compared to the same dose regimen. SEE ALSO: <a target="_blank" class="c-link c-message_attachment__title_link" href="https://www.businessinsider.in/tech/mobile/news/xiaomi-launches-mi-mix-4-its-first-under-display-camera-phone/articleshow/85231596.cms">Xiaomi debuts its first under-display camera on the Mi Mix 4</a> <a target="_blank" class="c-link c-message_attachment__title_link" href="https://www.businessinsider.in/tech/mobile/news/oneplus-teases-a-foldable-phone-announcement-clashing-with-samsungs-unpacked-event/articleshow/85233365.cms">OnePlus teases a foldable phone announcement clashing with Samsung’s Unpacked event</a>

DCGI approves study on mixing of Covaxin and Covishield  COVID-19 doses, say sources

The <keyword id="22366986" type="General" weightage="20" keywordseo="doctor-population-ratio" source="keywords">doctor-population ratio</keyword> in the country is 1:836, which is better than the <keyword id="20522854" type="General" weightage="20" keywordseo="WHO-standard" source="keywords">WHO standard</keyword> of 1:1000, Minister of State for Health Anupriya Patel told the Lok Sabha on Friday. According to the information provided by the <keyword id="20039511" type="General" weightage="100" keywordseo="National-Medical-Commission" source="keywords" meta.keywordsubtype="org" meta.entityname="National Medical Commission" meta.hostid="261" meta.entityid="National Medical Commission">National Medical Commission</keyword> (NMC), there are 13,86,136 <keyword id="20522855" type="General" weightage="20" keywordseo="allopathic-doctors" source="keywords">allopathic doctors</keyword> registered with the State Medical Councils and the National Medical Commission (NMC) as on July, 2024, Patel said in a written reply. "Assuming 80% availability of registered allopathic doctors and around 5.65 lakh <keyword id="20522856" type="General" weightage="20" keywordseo="AYUSH-doctors" source="keywords">AYUSH doctors</keyword>, the doctor-population ratio in the country is around 1:836 which is better than the WHO standard of 1:1000," Patel stated. She also said that there are 731 medical colleges in the country with an annual intake of 1,12,112 <keyword id="20585495" type="General" weightage="20" keywordseo="MBBS-seats" source="keywords">MBBS seats</keyword> as of now. Further, there are 72,627 <keyword id="22645227" type="General" weightage="20" keywordseo="PG-seats" source="keywords">PG seats</keyword> as of date, she said. Measures taken by the government to augment medical education facilities and to improve medical standards include <keyword id="22366985" type="General" weightage="20" keywordseo="Centrally-Sponsored-Scheme" source="keywords">Centrally Sponsored Scheme</keyword> (CSS) for establishment of new medical colleges by upgrading district/referral hospitals, under which 157 new medical colleges have been approved and 109 are already functional. Under the CSS, medical colleges have been upgraded to increase the number of MBBS (UG) and PG seats. Support has been provided for an increase of 4,977 MBBS seats in 83 colleges with an approved cost of Rs 5,972.20 crore, 4,058 PG seats in phase-I in 72 colleges with an approved cost of Rs 1,498.43 crore and 4,000 PG seats in phase-II in 65 colleges with an approved cost of Rs 4,478.25 crore. Besides, under "upgradation of government medical colleges by construction of super specialty blocks" component of Pradhan Mantri Swasthya Suraksha Yojana (PMSSY), 75 projects have been approved, of which 66 projects are complete. Under the Central Sector Scheme for setting up of new AIIMS, 22 AIIMS have been approved and undergraduate courses have started in 19 of these. Also, DNB qualification has been recognised for appointment as teaching faculty, to take care of shortage of faculty and there has been enhancement of age limit for appointment, extension or re-employment against posts of teachers/dean/principal/ director in medical colleges up to 70 years. <h2>Claims of Indians being unfit "extrapolated" </h2>Furthermore, Union Health Minister J P Nadda told the Lok Sabha today that WHO's recent report stating that half of India's adult population is physically unfit relied on data collected only from three states and one UT, and the results were extrapolated through a modelling technique indicating inbuilt methodological issues. Responding to a question, Nadda said the WHO defines 'sufficient physical activity' as 150 minutes of moderate intensity physical activities per week (brisk walk, lifting light load etc.) or 75 minutes of vigorous intensity activity per week (running, digging, construction work, outdoor games etc.). The activity level so quantified is based on a self-reported response to questions about physical activity lasting at least for 10 minutes. The National NCD Monitoring Survey of Indian Council of Medical Research (ICMR) 2020 has assessed, inter alia, physical activity amongst Indian adults and found that 58.7% had conformed to the WHO recommendations, Nadda told the Lok Sabha.

Doctor-population ratio in India better than WHO standard, says Govt

The Indian Council of Medical Research (<keyword id="6364396" type="General" weightage="20" keywordseo="icmr" source="Orion">ICMR</keyword>) has come up with the country's first Ethical Guidelines for the Application of Artificial Intelligence in Biomedical Research and <keyword id="6354525" type="General" weightage="100" keywordseo="healthcare" source="Orion">Healthcare</keyword> to provide an ethical framework for the development of <keyword id="6355999" type="General" weightage="20" keywordseo="ai" source="Orion">AI</keyword>-based tools which will benefit all stakeholders. According to a document drafted by the Department of Health Research and ICMR's Artificial Intelligence Cell, AI for health, to a large extent, depends on data obtained from human participants and invokes additional concerns related to potential biases, data handling, interpretation, autonomy, risk minimization, professional competence, data sharing, and confidentiality. "It is therefore imperative to have an ethical framework that addresses issues specific to AI for biomedical research and healthcare," the guidelines stated. The adoption of AI technology in healthcare is growing in India. However, AI as data-driven technology has many potential ethical challenges which include algorithmic transparency and explainability, clarity on liability, accountability and oversight, bias and discrimination, said ICMR Director General Dr Rajiv Behl. "The DHR-ICMR AI Cell has identified the need to develop these guiding ethical principles concerning artificial intelligence and machine learning-based tools. "These guidelines will provide the ethical framework for the development of AI-based tools which will benefit all stakeholders, including innovators, developers, patients, technologists, researchers, healthcare professionals, ethics committees, sponsors and funding agencies involved in research related to AI in biomedical research and healthcare," he said. NTAGI chief Dr N K Arora said the purpose of the guideline is to provide an ethical framework which can assist in the development, deployment, and adoption of AI-based solutions for biomedical research and healthcare delivery. The guidelines are intended for all stakeholders involved in research on artificial intelligence in healthcare, including creators, developers, technicians, researchers, clinicians, ethics committees, institutions, sponsors, and funding organizations. It includes separate sections addressing ethical principles for AI in health, guiding principles for stakeholders, the ethics review process, governance of artificial intelligence for healthcare and research, and the informed consent process involving human participants and their data. The guideline has been formulated after extensive discussions with subject experts, researchers and ethicists, said Dr Arora. The induction of AI into healthcare has the potential to be the solution for significant challenges like diagnosis and screening, therapeutics, preventive treatments, clinical decision-making, public health surveillance, complex data analysis, and predicting disease outcomes. This list is likely to grow in the future, the document said. The purpose of these guidelines is not to limit innovation or recommend any disease-specific diagnostic or therapeutic approach but to guide effective yet safe development, deployment and adoption of AI-based technologies in biomedical research and healthcare delivery, it said. These guidelines will be used by experts and ethics committees reviewing research proposals involving the use of AI-based tools and technologies. SEE ALSO: <a href="https://www.businessinsider.in/business/startups/news/ashneer-grovers-new-startup-crickpe-is-a-fantasy-sports-app-that-will-also-reward-cricketers/articleshow/98964195.cms">Ashneer Grover's new startup CrickPe is a fantasy sports app that will also reward cricketers</a> <a href="https://www.businessinsider.in/tech/news/you-will-soon-lose-your-legacy-blue-tick-on-twitter-heres-everything-you-need-to-know/articleshow/98960333.cms">You will soon lose your legacy blue tick on Twitter – here’s everything you need to know</a> <a href="https://www.businessinsider.in/tech/mobile/news/three-out-of-four-premium-smartphones-sold-in-2022-were-an-iphone/articleshow/98855033.cms">Three out of four premium smartphones sold in 2022 were an iPhone</a>

You Searched For "Indian Council of Medical Research ICMR" and got 12 results

ICMR's regional centre develops technology that can test for tuberculosis in just Rupees 35!

PTI

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Sperm or egg donor has no legal right on child, can't claim to be biological parent, says high court

PTI

Bread, butter, milk-based health drinks, cooking oils classified as ultra-processed food, ICMR advises restriction

Ankush Banerjee

Stillbirths are a hidden tragedy says ICMR as it seeks research funding

ANI

Almost 4 lakh diarrhoeal disease deaths can be averted if Jal Jeevan Mission meets target: WHO study

PTI

Sixth monkeypox case: Patient in stable condition at LNJP Hospital

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Biological E, Bharat Biotech together sitting on stockpile of 250 million COVID vaccine doses

PTI

Out of all cancer cases, 7.9% were found in children below 14 years, reveals ICMR report

IANS

DCGI approves study on mixing of Covaxin and Covishield COVID-19 doses, say sources

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Doctor-population ratio in India better than WHO standard, says Govt

Ira Alok Puranik

ICMR comes up with first ethical guidelines for application of AI in biomedical research, healthcare

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