Entertainment"Unfinished Business," about a small-business owner (Vaughn) trying to land a big deal mixed in with hijinks across Europe, debuted to $4.8 million at theaters.
Analysts expected the film to tank, making between $5 million and $6 million upon debut.
The film received terrible reviews for being downright unfunny and unfocused.
The movie had a reported $35 million production budget.
"Unfinished Business" is the actors latest comedic bomb at the box office.
After a string of big hits through 2009, Vaughn's last four films have flopped upon entry.
Here's a quick look back at Vaughn's wide releases since 2005's "Wedding Crashers" with Owen Wilson:
Unless Vaughn's with another leading star - Jennifer Aniston in "The Break-Up" or Reese Witherspoon in "Four Christmases" - he doesn't bring a big audience on his own.
The 44-year-old actor's next big role will be on season 2 of HBO's hit "True Detective" which will also star Colin Farrell and Rachel McAdams.
The role comes at a dire time when Vaughn's role as a viable standalone movie star is going to be heavily scrutinized after several flops in a row.