Cuoco is among the nominees for best performance by an actress in a musical or comedy TV series for her leading role on HBO Max's "The Flight Attendant."
The actress shared a video of herself Wednesday bursting into tears as she learned the news.
"Oh my God. I can't believe it," she told her husband, equestrian Karl Cook, who filmed her reaction.
A post shared by Kaley Cuoco (@kaleycuoco)
"The Flight Attendant," produced in part by Cuoco's Yes, Norman Productions, stars the actress as a flight attendant who gets caught up in a murder mystery.
Cuoco shared videos of her reactions to both nominations on Instagram.
"Thank you @goldenglobes#hfpa I will never ever forget this moment and I can't stop crying ... so proud of my entire team @flightattendantonmax ✈️ !!!!! YES NORMAN! ," wrote Cuoco, giving a little shout-out to her beloved dog, who died in January. (Cuoco coined her production studio after him in 2017.)
"The Flight Attendant" is Cuoco's first original series after spending over a decade on CBS' hit comedy, "The Big Bang Theory."
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Despite her costars Johnny Galecki and Jim Parsons being previously nominated for their work on the long-running series, Cuoco was never nominated for her popular role as Penny.
The 2021 Golden Globes will air Sunday, February 28 at 8 p.m. ET/PT on NBC.
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