The 50-something patient was vaccinated on Tuesday morning at the hospital in Goyang, just outside of Seoul's northwestern border.
The patient began to show symptoms of heart failure and difficulty in breathing by the afternoon but recovered after being put under emergency care, reports Yonhap news agency.
The symptoms recurred on Wednesday morning before the patient died.
Health officials said they have yet to determine whether the patient suffered side effects from the vaccine.
The patient's pre-existing conditions included heart problems, diabetes and a stroke.
AstraZeneca is yet to react to the incident.
The Daily Mail, quoting new findings, reported earlier this week that just one shot of
Public health officials told Ministers in the UK that the remarkable results apply for both the
"The strong results for the Oxford vaccine are a rebuke to the German authorities, which last month advised against its use in the over-65s," the report mentioned.
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