The 30-share BSE index was trading 254.72 points or 0.55 per cent lower at 45,848.78.
Similarly, the
On the other hand, Maruti, Nestle India, Titan and PowerGrid were among the gainers.
In the previous session, Sensex ended 494.99 points or 1.09 per cent higher at its
Foreign portfolio investors (FPIs) were net buyers in the capital market as they purchased shares worth Rs 3,564.23 crore on a net basis on Wednesday, according to provisional exchange data.
"Domestic markets do not appear inspiring at the moment as global markets are trading in red," said Binod Modi Head-Strategy at Reliance Securities.
US equities finished lower mainly led by selling pressure in technology stocks, he added.
Elsewhere in Asia, bourses in Hong Kong, Seoul and Tokyo were trading in the red in mid-session deals, while Shanghai was in the positive territory.
Meanwhile, the global oil benchmark Brent crude futures were trading 0.53 per cent higher at USD 49.12 per barrel.
SEE ALSO: Facebook hit with 2 massive antitrust lawsuits from the FTC and 46 states seeking to spin off Instagram and WhatsApp
Airbnb prices IPO at $68 per share, will raise $3.5 billion