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The sacked employees will receive severance packages and the company will "reprioritise' remaining recruitment staff.
Twitter had earlier announced to halt most hiring across divisions.
As Twitter paused hiring, the micro-blogging platform last month shifted employees away from audio Spaces, Communities and newsletters verticals for areas that "will have the greatest positive impact to the public conversation".
Agrawal had said that the company will also be reviewing all extended offers to determine criticality and those that should be pulled back.
"We are not planning company-wide layoffs, but leaders will continue making changes to their organizations to improve efficiencies as needed," Agrawal had said in a memo to employees.
Twitter has paused most hiring and backfills, except for business critical roles as determined by 'Staff' members.
"Some have been asking why a alame-duck' CEO would make these changes if we're getting acquired anyway. While I expect the deal to close, we need to be prepared for all scenarios and always do what's right for Twitter," Agrawal had said.
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