Influenza vaccine may provide roadmap to prevent Covid-19: Study
In the study, published in the Journal of the American College of Cardiology, the research team evaluated whether existing
Furthermore, seasonal influenza epidemics have been associated with population-level increases in cardiovascular hospitalisation and mortality.
For these reasons, clinical guidelines recommend the general population receive their flu vaccination annually to reduce the risk of
Research has shown that viral respiratory infections such as seasonal influenza and Covid-19 are risk factors for cardiovascular disease.
Patients with cardiovascular disease are also at a higher risk of complications following viral respiratory infections, including increased morbidity, mortality and health care utilization.
Current data suggests influenza infection and the novel coronavirus share similar symptoms at the outset, primarily fever, cough and shortness of breath. However, Covid-19 appears to be more contagious than the flu.
"Although Covid-19 and other respiratory virus infections are associated with acute myocardial infarction and other cardiovascular events, influenza has the best evidence of a safe
Several observational and small, randomized studies have suggested that influenza vaccination may serve as a preventative measure against adverse cardiovascular outcomes.
AdvertisementHowever, despite international guidelines recommending routine influenza and pneumococcal vaccination for patients with cardiovascular disease, uptake is substantially lacking and often deprioritised, including at the time of cardiovascular hospitalisation.
There are currently three international cardiovascular outcome trials examining the cardioprotective effects of different influenza vaccine formulations, according to the team.
"Three large ongoing influenza vaccine cardiovascular outcome trials have an opportunity to contribute further to our understanding of the underlying comorbidities in these patients that may be driving morbidity and mortality associated with Covid-19 infection," Udell said.
"While developing new vaccines, we will also definitively learn soon whether influenza vaccination is an effective, low-cost, widely available therapy that reduces cardiovascular risk, which may further help prevent fatal and nonfatal cardiovascular complications of Covid-19," Udell noted.
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