Gilead just handed a revolutionary kind of cancer treatment a $12 billon endorsement
REUTERS/Suzanne Plunkett
The drugmaker's therapy that's a few months away from a possible approval is a highly personalized cancer treatments called CAR T-cell therapy. It's a form of cancer immunotherapy - or a therapy that harnesses the body's immune system to take on cancer cells.
For Gilead, which is known for its HIV and hepatitis C medications, this is an entirely new area of cancer development.
"The field of cell therapy has advanced very quickly, to the point where the science and technology have opened a clear path toward a potential cure for patients," Gilead CEO John Milligan said in a news release. "We are greatly impressed with the Kite team and what they have accomplished, and share their belief that cell therapy will be the cornerstone of treating cancer."
Here's why cell therapies could be game-changing
Short for chimeric antigen receptor T-cell therapy, CAR-T treatment removes a person's cells from the body, reengineers them, and then puts the cells back in the body, where they can attack cancer cells. That means that a person's own cells are the therapy, which makes it more difficult to manufacture than your average pill.
In July, a Food and Drug Administration panel voted in favor of approving one of these treatments made by Novartis. One of the panelists called it "most exciting thing I've seen in my lifetime." The FDA is expected to decide whether to approve that therapy, a treatment for pediatric acute lymphoblastic lymphoblastic leukemia, by October.
Gilead won't have to wait long to see if the FDA will approve Kite's leading cell therapy, which is called axicabtagene ciloleucel or axi-cel. In November, Kite is expected to get an answer from the FDA regarding its CAR-T treatment for a type of blood cancer called aggressive B-cell non-Hodgkin lymphoma. In data Kite released in February, the company found that out of 101 patients, 36% had a complete response to the treatment after six months.
The one-time treatments won't come cheap. While companies might price the drug based on how well it works, axi-cel's price tag could still be $325,000. Analysts expect the therapy to generate $1.7 billion in sales by 2022.
While its axi-cel program is the farthest along, Kite's also working on another CAR-T cell therapy that's in clinical trials to treat multiple myeloma, another form of blood cancer. The company's also working on cell therapies to treat solid tumors that are still in early clinical trials.
- A centenarian who starts her day with gentle exercise and loves walks shares 5 longevity tips, including staying single
- A couple accidentally shipped their cat in an Amazon return package. It arrived safely 6 days later, hundreds of miles away.
- Colon cancer rates are rising in young people. If you have two symptoms you should get a colonoscopy, a GI oncologist says.
- Having an regional accent can be bad for your interviews, especially an Indian one: study
- Dirty laundry? Major clothing companies like Zara and H&M under scrutiny for allegedly fuelling deforestation in Brazil
- 5 Best places to visit near Darjeeling
- Climate change could become main driver of biodiversity decline by mid-century: Study
- RBI initiates transition plan: Small finance banks to ascend to universal banking status
- JNK India IPO allotment date
- JioCinema New Plans
- Realme Narzo 70 Launched
- Apple Let Loose event
- Elon Musk Apology
- RIL cash flows
- Charlie Munger
- Feedbank IPO allotment
- Tata IPO allotment
- Most generous retirement plans
- Broadcom lays off
- Cibil Score vs Cibil Report
- Birla and Bajaj in top Richest
- Nestle Sept 2023 report
- India Equity Market