Cruella's entire bit in the Disney universe has been that she steals puppies to have them skinned and turned into fur coats.
The live-action prequel alludes to this, with Cruella even saying that the Baroness' three prized Dalmatians would make great coats. The mention of killing dogs visibly horrifies Jasper and Cruella insists that she's joking.
Shortly later, Cruella shows up at her own fashion show in a Dalmatian-inspired look and the Baroness is convinced that she killed her dogs. (She didn't.)
Instead, this Cruella is strangely very pro-dog, which goes against everything the animated film had viewers believe. By the film's end, she takes in the Baroness' three Dalmatians. If the plan is for Disney to do a follow-up sequel, it's currently unclear whether or not Cruella will eventually take a turn and lean into the notorious puppy murdering fashion icon that made her one of the Mouse House's cruelest villains.