Study Reveals How Cancer Cells Spread From Primary Tumour
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According to a recent study that appeared in Nature Cell Biology journal, researchers have found a signalling pathway in The study also sheds light on the spread of cancer to distant tissues and organs, which also complicates cancer treatment.
A cancer cell must first break through the surrounding connective tissue, also known as the
The cancer forms short-lived, foot-like protrusions, known as
Invadopodia release enzymes that degrade the extracellular matrix (ECM). Other protrusions pull the cancer cell along, much like a locomotive pulls a train.
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The invading cancer cell relies on the cycle of invadopodium formation/disappearance to successfully travel from the tumour. It enters nearby blood vessels to spread in other parts of the body.
Louis Hodgson, an assistant professor at
Image: Thinstock
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