The Good Hotel will float on the Thames, and it will be accessible by bridge.
Plans suggest the former detention centre will reside in the Royal Docks, though some residents have lodged complaints about a potential increase in noise and traffic, The Daily Mail reports.
The roof garden, inspired by New York's revamped railway, The High Line Bridge, will be open to the public.
The interior of the hotel has undergone a makeover for its move out of Amsterdam.
next slide will load in 15 secondsSkip AdSkip AdThe Good Hotel wants to transform more than just prisons: it works to give the long-term unemployed 10-month placements with training.
Food and drink will be locally sourced from across the capital.
The floating hotel's terrace will provide views of London's unique skyline, including the O2 Centre.
Former cells are now unrecognisable, having been given modern makeovers.
Founded by Marten Dresen in 2012, The Good Hotel Group has plans to expand to eight more locations worldwide by 2020.