Ulrich, who stars as FP Jones (Sprouse's on-screen father) on the CW show, recently answered questions from fans during an Instagram live with girlfriend Megan Blake Irwin.
One person asked the 50-year-old actor: "Do you think that Cole Sprouse and Lili Reinhart are a cute couple?"
"I think they were a very cute couple," Skeet said in response.
Then, Irwin chimed in and said, "They were a very cute couple," emphasizing the word "were."
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"They're both beautiful people," she added.
Their use of the past tense led fans to believe that Reinhart and Sprouse, who star as on-screen couple Betty Cooper and Jughead Jones, ended their relationship.
You can see the moment, which was captured by a fan account on Twitter, in the video below.
This isn't the first time the two stars have faced breakup speculation.
Reinhart and Sprouse reportedly started dating in 2017, the same year that "Riverdale" premiered on The CW. In July 2019, Us Weekly reported that they broke up. An unnamed source also told E! News that the actors split "earlier this summer."
"Don't believe everything you read on the internet, kids. And news sources should try a little harder to be less vile. 'Reliable sources' can kiss my a--," she wrote on Twitter.
"I tolerate a lot of rumors and slander from people online claiming to be my fans. Fans who feel entitled to my privacy precisely because I never indulge them," he wrote on his Instagram story. "But attacking my friends, baseless accusations, leaking my address and sending death threats are all qualities of insanity and fanaticism. Choose humanity, stop being [clowns]."
He continued: "When I first stepped into a public relationship this was one of the foreseeable consequences. And while I truly never intended to indulge any part of my private life to the ravenous horde, it's clear my restraint in updating them has allowed them to push their own agenda onto my habits and lifestyle."
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Reinhart also shared a message on her Instagram, writing: "Dear everyone on social media, don't put people down for the sake of putting them down. Don't be a f---ing a--hole. The world doesn't need any more of that s---."
At the time, E! News reported that they were still together, despite fans thinking otherwise.
"Twitter is such a vile place," she wrote. "It's so easy to say s--- behind your f---ing phone, isn't it? This is why people choose to keep their relationships private... this is why people don't have social media.. because of this bullying."
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She added that "attacking someone for literally no reason, just for the sake of a f---ing twitter trend" is unnecessary.
Representatives for Reinhart and Sprouse didn't immediately respond to Insider's requests for comment.
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