The pick: Los Angeles Rams record the first penalty of the game ($150 to win $100)
The logic: Three things in play here. First, this is the first Super Bowl for most players on the Rams roster, so it'd be understandable for them to be a bit jumpy compared to the Patriots.
Second, the Rams are likely to get the ball first, as the Patriots seem to win every coin toss they participate in, and almost always choose to defer. Offensive penalties, either a holding or a false start, feel more likely than a pass interference early on in the game.
Finally, after the Rams got away with the no-call of the century in the NFC Championship, expect the officials to remind them early that they weren't going to get away with the crime twice.