The Steelers officially moved superstar T.J. Watt to the IR this week, leaving a mighty hole in their defensive front. While Minkah Fitzpatrick can still cause plenty of trouble, the Patriots should be able to get their act together enough to get past Pittsburgh.Last week, quarterback Mitch Trubisky and the Steelers' offense managed just 20 points in regulation despite their defense securing five turnovers to give them solid field position and ample possessions. Those are the types of missed opportunities that Bill Belichick's teams usually make you pay for.The Ravens weren't tested all that much against the New York Jets, but Lamar Jackson should have a huge year provided he can stay on the field all season. The Dolphins got off to a strong start against the Patriots, but a road trip to Baltimore is no easy task.Tom Brady is 0-4 in regular season matchups against the New Orleans Saints since his arrival in Tampa Bay. The last one of those losses was an embarrassing 9-0 defeat in Tampa, where Brady was outdueled by Taysom Hill of all people.Brady does have plenty of potential to finally break out a revenge game against his late-career divisional foe, but the trend is strong enough that I will wait for him to prove he can do it before backing the Buccaneers in this spot.This is a tough game to get a read on, as the Colts might be very good despite a mediocre showing against the Texans last week. Still, this is a divisional game and the Jaguars should be hungry to secure a home win after last year's season from hell.The half-point hook was the tiebreaker here, but it might be best to put your money elsewhere unless you have a really strong read on this game.Joe Flacco and the Jets looked absolutely lost last weekend, but Jacoby Brissett should not be a touchdown favorite against anybody.The Carolina Panthers might be a dead team walking, with a placeholder quarterback and a head coach waiting to be fired.Meanwhile, the vibes in the New York Giants locker room are absolutely electric.Can't bet against that.The Detroit Lions showed plenty of fight in a 38-35 loss to the Philadelphia Eagles last week. While the defense certainly needs some work — and could be susceptible to another good day from Commanders QB Carson Wentz — Detroit might have one of the best rushing attacks in the league. If D'Andre Swift can keep the Lions offense moving, this should be a win for the home team.Matthew Stafford did not look good against the Buffalo Bills to start the season. He's had 10 days to get healthy, and the Rams could be set for a great bounce-back game, but this Falcons team doesn't look like one to just roll over. Until Stafford's arm is back in playing shape, I won't be laying double-digit points with Los Angeles.The 49ers Week 1 loss to the Bears in Chicago was something of a wash. Literally. Through monsoon conditions, it's difficult to judge the potential of quarterback Trey Lance, who has taken over the San Francisco offense this year.But even dismissing the disappointing showing in Chicago, there's no reason for Lance, still largely unproven, to be a touchdown favorite against a Seahawks team that looked better than anyone expected last week.Sure, Seattle is at risk of a let-down game after the high-running emotions from Week 1 — taking down former franchise QB Russell Wilson to start the season — but Geno Smith looked good with the football, and Lance still hasn't shown anything that indicates he's a world-beater yet.Joe Burrow turned the ball over five times against the Pittsburgh Steelers last week. Despite that, if not for a blocked extra point late in the fourth quarter, Burrow and the Bengals would have escaped Pittsburgh with a win.Meanwhile, the Cowboys are without quarterback Dak Prescott, and will instead be leaning on Cooper Rush to lead the offense. Even with a brilliant showing from the Dallas defense, the Bengals should walk all over them.The Broncos struggled on the road in Seattle last weekend, but look for Denver to open things up for Russell Wilson's first home game at Mile High Stadium.Against a Texans team that outplayed their expectations last week, Wilson and the Broncos have a great look at a get-right game. This should not be close.Aaron Rodgers still doesn't have anyone to throw to, which is admittedly a problem.But the Bears won't have the pouring rain to serve as an equalizer in this game, and Rodgers should take care of business at home against a divisional foe, which he has repeatedly said he owns.He's not wrong — the Packers have beaten the Bears in six straight outings, the last four of which have all come by double digits.The Bills looked like the best team in football last week. Still, this line feels like an overreaction to Week 1.Had this game been played last week, it feels like the spread would be, at most, Buffalo -6. Instead, the Bills played a near-perfect game, and the Titans looked atrocious. When a line moves that much based on one week of action, it's usually smart to take the side that got the extra juice.Justin Jefferson is going to be a problem this year, as he already has been in years past. This should be a stellar game, with two intriguing offenses going up against defenses with something to prove.