In July 2003, there were 71 cases of monkeypox reported to the Centers for Disease Control and Prevention. The cases came from several states: Wisconsin had 39 cases; Indiana, 16; Illinois, 12; Missouri, 2; Kansas, 1; Ohio, 1. The majority of patients were exposed to prairie dogs. Some patients were exposed in premises where prairie dogs were kept, and others were exposed to persons with monkeypox, according to the archived CDC website. Following investigations, the CDC blamed the outbreak on monkeypox-positive animals that were intermingling with other animals and humans in different settings. In this outbreak, the rapid and widespread distribution of monkeypox-infected and potentially infected imported wild animals to distributors and potential buyers in several settings (e.g., pet stores, swap meets, and wild animal trade centers) in the United States and to other countries enabled epizootic spread through multiple states before effective interventions could be implemented, the CDC said. Those who contracted monkeypox – like the Kautzer family did – were ordered to quarantine. Doctors used the smallpox vaccine to prevent the transmission of monkeypox. Smallpox is more severe than monkeypox, but both have similar symptoms. By June 2003, at least 30 people received the smallpox vaccine, including 28 adults and two children, according to the archived CDC site. The vaccine was given pre-exposure to some and post-exposure to others. No serious adverse events were reported following smallpox vaccination, according to the CDC site. President Joe Biden said Sunday the detection of monkeypox in the United States is something that everybody should be concerned about.It is a concern in that if it were to spread it would be consequential, the president told reporters at Osan Air Base in South Korea, per The Associated Press. They haven't told me the level of exposure yet but it is something that everybody should be concerned about, he added. The WHO said Saturday it expects more cases of monkeypox to be identified and plans to deliver recommendations for mitigating spread.